Season:
← 2009 2011 →
| Date | Rank | Opponent | Stadium | Result | Record |
| September 4 | #1 | San Jose State | Bryant–Denny Stadium | W 48–3 | 1-0 |
| September 11 | #1 | #18 Penn State | Bryant–Denny Stadium | W 24–3 | 2-0 |
| September 18 | #1 | at Duke | Wallace Wade Stadium | W 62–13 | 3-0 |
| September 25 | #1 | at #10 Arkansas | Donald W. Reynolds Stadium | W 24–20 | 4-0 |
| October 2 | #1 | #7 Florida | Bryant–Denny Stadium | W 31–6 | 5-0 |
| October 9 | #1 | at #19 South Carolina | Williams-Brice Stadium | L 21–35 | 5-1 |
| October 16 | #8 | Ole Miss | Bryant–Denny Stadium | W 23–10 | 6-1 |
| October 23 | #7 | at Tennessee | Neyland Stadium | W 41–10 | 7-1 |
| November 6 | #5 | at #10 LSU | Tiger Stadium | L 21–24 | 7-2 |
| November 13 | #11 | #17 Mississippi State | Bryant–Denny Stadium | W 30–10 | 8-2 |
| November 18 | #10 | Georgia State | Bryant–Denny Stadium | W 63–7 | 9-2 |
| November 26 | #9 | #2 Auburn | Bryant–Denny Stadium | L 27–28 | 9-3 |
| Capital One Bowl | |
| January 1 | #15 | #7 Michigan State | Citrus Bowl | W 49–7 | 10-3 |
