Team: Season:
| Date | Opponent | Stadium | Results |
| Thursday, Sept. 3 | at Utah | Rice-Eccles Stadium | L 17-24 (0-1) |
| Saturday, Sept. 12 | Oregon State | Michigan Stadium | W 35-7 (1-1) |
| Saturday, Sept. 19 | UNLV | Michigan Stadium | W 28-7 (2-1) |
| Saturday, Sept. 26 | BYU | Michigan Stadium | W 31-0 (3-1) |
| Saturday, Oct. 3 | at Maryland* | Byrd Stadium | W 28-0 (4-1) |
| Saturday, Oct. 10 | Northwestern* | Michigan Stadium | W 38-0 (5-1) |
| Saturday, Oct. 17 | Michigan State** | Michigan Stadium | L 23-27 (5-2) |
| Saturday, Oct. 24 | Open Date | | |
| Saturday, Oct. 31 | at Minnesota** | TCF Bank Stadium | W 29-26 (6-2) |
| Saturday, Nov. 7 | Rutgers* | Michigan Stadium | W 49-16 (7-2) |
| Saturday, Nov. 14 | at Indiana* | Memorial Stadium | W 48-41 2OT (8-2) |
| Saturday, Nov. 21 | at Penn State* | Beaver Stadium | W 28-16 (9-2) |
| Saturday, Nov. 28 | Ohio State** | Michigan Stadium | L 13-42 (9-3) |
| Friday, Jan. 1 | vs. Florida | Orlando Citrus Bowl Stadium | W 41-7 (10-3) |
** – Rivalry and Conference Game
* – Conference Game
