Team: Season:
| Date | Opponent | Stadium | Results |
| Saturday, Sept. 5 | Texas | Notre Dame Stadium | W 38-3 (1-0) |
| Saturday, Sept. 12 | at Virginia | Scott Stadium | W 34-27 (2-0) |
| Saturday, Sept. 19 | Georgia Tech | Notre Dame Stadium | W 30-22 (3-0) |
| Saturday, Sept. 26 | UMass | Notre Dame Stadium | W 62-27 (4-0) |
| Saturday, Oct. 3 | at Clemson | Memorial Stadium | L 22-24 (4-1) |
| Saturday, Oct. 10 | Navy | Notre Dame Stadium | W 41-24 (5-1) |
| Saturday, Oct. 17 | USC | Notre Dame Stadium | W 41-31 (6-1) |
| Saturday, Oct. 24 | Open Date | | |
| Saturday, Oct. 31 | at Temple | Lincoln Financial Field | W 24-20 (7-1) |
| Saturday, Nov. 7 | at Pittsburgh | Heinz Field | W 42-30 (8-1) |
| Saturday, Nov. 14 | Wake Forest | Notre Dame Stadium | W 28-7 (9-1) |
| Saturday, Nov. 21 | Boston College | Fenway Park | W 19-16 (10-1) |
| Saturday, Nov. 28 | at Stanford | Stanford Stadium | L 36-38 (10-2) |
| Friday, Jan. 1 | vs. Ohio State | University of Phoenix Stadium | L 28-44 (10-3) |
