Team:
| Date | Team | Time (ET) | TV | Results |
| Preseason | ||||
| Saturday, Aug 15 | at Houston | 8:00 p.m. | KPIX 5 | L 10-23 (0-1) |
| Sunday, Aug 23 | vs. Dallas | 8:00 p.m. | KPIX 5 | W 23-6 (1-1) |
| Saturday, Aug 29 | at Denver | 9:00 p.m. | KPIX 5 | L 12-19 (1-2) |
| Thursday, Sept 3 | vs. San Diego | 10:00 p.m. | KPIX 5 | W 14-12 (2-2) |
| Regular Season | ||||
| Date | Team | Time (ET) | TV | Results |
| Monday, Sept 14 | vs. Minnesota | 10:20 p.m. | ESPN | W 20-3 (1-0) |
| Sunday, Sept 20 | at Pittsburgh | 1:00 p.m. | FOX | L 18-43 (1-1) |
| Sunday, Sept 27 | at Arizona | 4:05 p.m. | FOX | L 7-47 (1-2) |
| Sunday, Oct 4 | vs. Green Bay | 4:25 p.m. | FOX | L 3-17 (1-3) |
| Sunday, Oct 11 | at New York Giants | 8:30 p.m. | NBC | L 27-30 (1-4) |
| Sunday, Oct 18 | vs. Baltimore | 4:25 p.m. | CBS | W 25-20 (2-4) |
| Thursday, Oct 22 | vs. Seattle | 8:25 p.m. | CBS/NFL Network | L 3-20 (2-5) |
| Sunday, Nov 1 | at St. Louis | 1:00 p.m. | FOX | L 6-27 (2-6) |
| Sunday, Nov 8 | vs. Atlanta | 4:05 p.m. | FOX | W 17-16 (3-6) |
| Sunday, Nov 15 | Bye Week | |||
| Sunday, Nov 22 | at Seattle | 4:25 p.m. | FOX | L 13-29 (3-7) |
| Sunday, Nov 29 | vs. Arizona | 4:05 p.m. | FOX | L 13-19 (3-8) |
| Sunday, Dec 6 | at Chicago | 1:00 p.m. | FOX | W 26-20 OT (4-8) |
| Sunday, Dec 13 | at Cleveland | 1:00 p.m. | FOX | L 10-24 (4-9) |
| Sunday, Dec 20 | vs. Cincinnati | 8:30 p.m. | NBC | L 14-24 (4-10) |
| Sunday, Dec 27 | at Detroit | 1:00 p.m. | FOX | L 17-32 (4-11) |
| Sunday, Jan 3 | vs. St. Louis | 4:25 p.m. | FOX | W 19-16 OT (4-12) |