Team: Season:
| Date | Opponent | Stadium | Results |
| Saturday, Sept. 5 | Alabama | AT&T Stadium, Arlington | L 17-35 (1-0) |
| Saturday, Sept. 12 | Miami (OH) | Camp Randall Stadium | W 58-0 (1-1) |
| Saturday, Sept. 19 | Troy | Camp Randall Stadium | W 28-3 (2-1) |
| Saturday, Sept. 26 | Hawaii | Camp Randall Stadium | W 28-0 (3-1) |
| Saturday, Oct. 3 | Iowa** | Camp Randall Stadium | L 6-10 (3-2) |
| Saturday, Oct. 10 | at Nebraska** | Memorial Stadium | W 23-21 (4-2) |
| Saturday, Oct. 17 | Purdue* | Camp Randall Stadium | W 24-7 (5-2) |
| Saturday, Oct. 24 | at Illinois* | Memorial Stadium | W 24-13 (6-2) |
| Saturday, Oct. 31 | Rutgers* | Camp Randall Stadium | W 48-20 (7-2) |
| Saturday, Nov. 7 | at Maryland* | Byrd Stadium | W 31-24 (8-2) |
| Saturday, Nov. 14 | Open Date | | |
| Saturday, Nov. 21 | Northwestern* | Camp Randall Stadium | L 7-13 (8-3) |
| Saturday, Nov. 28 | at Minnesota** | TCF Bank Stadium | W 31-21 (9-3) |
| Wednesday, Dec. 30 | vs. USC | Qualcomm Stadium | W 23-21 (10-3) |
** – Rivalry and Conference Game
* – Conference Game
