Team: Season:
| Date | Opponent | Stadium | Time (ET)/TV | Tickets/Results |
| Saturday, Sept. 3 | Hawaii | Michigan Stadium | 12:00 p.m./ESPN | W 63-3 (1-0) |
| Saturday, Sept. 10 | UCF | Michigan Stadium | 12:00 p.m./ABC | |
| Saturday, Sept. 17 | Colorado | Michigan Stadium | 3:30 p.m./BTN | |
| Saturday, Sept. 24 | Penn State | Michigan Stadium | TBA | |
| Saturday, Oct. 1 | Wisconsin | Michigan Stadium | TBA | |
| Saturday, Oct. 8 | at Rutgers | High Point Solutions Stadium | TBA | |
| Saturday, Oct. 15 | Bye Week | | | |
| Saturday, Oct. 22 | Illinois | Michigan Stadium | 3:30 p.m./TBA | |
| Saturday, Oct. 29 | at Michigan State | Spartan Stadium | TBA | |
| Saturday, Nov. 5 | Maryland | Michigan Stadium | TBA | |
| Saturday, Nov. 12 | at Iowa | Kinnick Stadium | 8:00 p.m./TBA | |
| Saturday, Nov. 19 | Indiana | Michigan Stadium | TBA | |
| Saturday, Nov. 26 | at Ohio State | Ohio Stadium | TBA | |
| Saturday, Dec. 3 | Big Ten Championship Game | Lucas Oil Stadium | 8:00 p.m./FOX | |
