Team: Season:
| Date | Opponent | Stadium | Time (ET)/TV | Tickets/Results |
| Saturday, Sept. 3 | Bowling Green | Ohio Stadium | 12:00 p.m./BTN | W 77-10 (1-0) |
| Saturday, Sept. 10 | Tulsa | Ohio Stadium | 3:30 p.m./ABC | |
| Saturday, Sept. 17 | at Oklahoma | Gaylord Family Oklahoma Memorial Stadium | 7:30 p.m./FOX | |
| Saturday, Sept. 24 | Open Date | | | |
| Saturday, Oct. 1 | Rutgers | Ohio Stadium | 12:00 p.m./TBA | |
| Saturday, Oct. 8 | Indiana | Ohio Stadium | TBA | |
| Saturday, Oct. 15 | at Wisconsin | Camp Randall Stadium | 8:00 p.m./TBA | |
| Saturday, Oct. 22 | at Penn State | Beaver Stadium | 8:00 p.m./TBA | |
| Saturday, Oct. 29 | Northwestern | Ohio Stadium | 5:30 p.m./TBA | |
| Saturday, Nov. 5 | Nebraska | Ohio Stadium | 8:00 p.m./TBA | |
| Saturday, Nov. 12 | at Maryland | Byrd Stadium | TBA | |
| Saturday, Nov. 19 | at Michigan State | Spartan Stadium | TBA | |
| Saturday, Nov. 26 | Michigan | Ohio Stadium | TBA | |
| Saturday, Dec. 3 | Big Ten Championship Game | Lucas Oil Stadium | 8:00 p.m./FOX | |
