Team: Season:
| Date | Opponent | Stadium | Time (ET)/TV | Tickets/Results |
| Saturday, Sept. 3 | UC Davis | Autzen Stadium | 5:00 p.m./Pac-12N | W 53-28 (1-0) |
| Saturday, Sept. 10 | Virginia | Autzen Stadium | 10:30 p.m./ESPN | W 44-26 (2-0) |
| Saturday, Sept. 17 | at Nebraska | Memorial Stadium | 3:30 p.m./ABC | L 32-35 (2-1) |
| Saturday, Sept. 24 | Colorado | Autzen Stadium | 5:30 p.m./Pac-12N | |
| Saturday, Oct. 1 | at Washington State | Martin Stadium | TBA | |
| Saturday, Oct. 8 | Washington | Autzen Stadium | TBA | |
| Saturday, Oct. 15 | Bye Week | | | |
| Friday, Oct. 21 | at Cal | California Memorial Stadium | 10:30 p.m./ESPN | |
| Saturday, Oct. 29 | Arizona State | Autzen Stadium | TBA | |
| Saturday, Nov. 5 | at USC | LA Memorial Coliseum | TBA | |
| Saturday, Nov. 12 | Stanford | Autzen Stadium | TBA | |
| Saturday, Nov. 19 | at Utah | Rice-Eccles Stadium | TBA | |
| Saturday, Nov. 26 | at Oregon State | Reser Stadium | TBA | |
| Friday, Dec. 2 | Pac-12 Championship Game | Levi's Stadium | 9:00 p.m./FOX | |
