Season:
| Date | Rank | Opponent | Stadium | Results (Time/TV) |
|---|---|---|---|---|
| September 4 | NR | East Tennessee State | Vanderbilt Stadium | L 3-23 (0-1) |
| September 11 | NR | at Colorado State | Canvas Stadium | W 24–21 (1-1) |
| September 18 | NR | Stanford | Vanderbilt Stadium | L 23-41 (1-2) |
| September 25 | NR | #2 Georgia | Vanderbilt Stadium | L 0-62 (1-3) |
| October 2 | NR | UConn | Vanderbilt Stadium | W 30–28 (2-3) |
| October 9 | NR | at #20 Florida | Ben Hill Griffin Stadium | L 0-42 (2-4) |
| October 16 | NR | at South Carolina | Williams-Brice Stadium | L 20-41 (2-5) |
| October 23 | NR | Mississippi State | Vanderbilt Stadium | L 6-45 (2-6) |
| October 30 | NR | Missouri | Vanderbilt Stadium | L 28-37 (2-7) |
| November 13 | NR | Kentucky | Vanderbilt Stadium | L 17-34 (2-8) |
| November 20 | NR | at #12 Ole Miss | Vaught-Hemingway Stadium | L 17-31 (2-9) |
| November 27 | NR | at Tennessee | Neyland Stadium | L 21-45 (2-10) |