Season:
| Date | Rank | Opponent | Stadium | Time (CT)/TV | Results |
|---|---|---|---|---|---|
| Saturday, Sept. 3 | NR | Louisiana-Monroe | DKR-Texas Memorial Stadium | 7:00 p.m./LHN | W 52-10 (1-0) |
| Saturday, Sept. 10 | NR | #1 Alabama | DKR-Texas Memorial Stadium | 11:00 a.m./FOX | L 19-20 (1-1) |
| Saturday, Sept. 17 | #21 | UTSA | DKR-Texas Memorial Stadium | 7:00 p.m./LHN | W 41-20 (2-1) |
| Saturday, Sept. 24 | #22 | at Texas Tech | Jones AT&T Stadium | 2:30 p.m./ABC | L 34-37 OT (2-2) |
| Saturday, Oct. 1 | NR | West Virginia | DKR-Texas Memorial Stadium | 2:30 p.m./ESPN | W 38-20 (3-2) |
| Saturday, Oct. 8 | NR | vs Oklahoma | Cotton Bowl Stadium | 11:00 a.m./ABC | W 49-0 (4-2) |
| Saturday, Oct. 15 | #22 | Iowa State | DKR-Texas Memorial Stadium | 11:00 a.m./ABC | W 24-21 (5-2) |
| Saturday, Oct. 22 | #20 | at #11 Oklahoma State | Boone Pickens Stadium | 2:30 p.m./ABC | |
| Saturday, Nov. 5 | at Kansas State | Bill Snyder Family Stadium | TBA | ||
| Saturday, Nov. 12 | TCU | DKR-Texas Memorial Stadium | TBA | ||
| Saturday, Nov. 19 | at Kansas | David Booth Kansas Memorial Stadium | TBA | ||
| Saturday, Nov. 26 | Baylor | DKR-Texas Memorial Stadium | TBA | ||
| Saturday, Dec. 3 | Big 12 Championship Game | AT&T Stadium | TBA |