Season:
| Date | Rank | Opponent | Stadium | Time/TV | Results |
|---|---|---|---|---|---|
| Saturday, Aug. 26 | Hawaii | Vanderbilt Stadium | TBA | ||
| Saturday, Sept. 2 | Alabama A&M | Vanderbilt Stadium | TBA | ||
| Saturday, Sept. 9 | at Wake Forest | Truist Field | TBA | ||
| Saturday, Sept. 16 | at UNLV | Allegiant Stadium | TBA | ||
| Saturday, Sept. 23 | Kentucky | Vanderbilt Stadium | TBA | ||
| Saturday, Sept. 30 | Missouri | Vanderbilt Stadium | TBA | ||
| Saturday, Oct. 7 | at Florida | Ben Hill Griffin Stadium | TBA | ||
| Saturday, Oct. 14 | Georgia | Vanderbilt Stadium | TBA | ||
| Saturday, Oct. 28 | at Ole Miss | Vaught-Hemingway Stadium | TBA | ||
| Saturday, Nov. 4 | Auburn | Vanderbilt Stadium | TBA | ||
| Saturday, Nov. 11 | at South Carolina | Williams-Brice Stadium | TBA | ||
| Saturday, Nov. 25 | at Tennessee | Neyland Stadium | TBA |