Florida State and Louisville will be an interesting matchup, with both teams having explosive quarterbacks in Lamar Jackson and Deondre Francois. This game could come down to which defense can create the most turnovers. The Seminoles will be without safety Derwin James, who will miss five to seven weeks with a knee injury.
Fueled by Sports predicts that Louisville will win the game 45-38 behind another strong performance from Jackson and their explosive offense.
Campus Insiders predicts that the Louisville Cardinals will win the game.
The two teams will square off on Saturday at 12:00 p.m. ET on ABC.